Trends in corneal transplantation from 2001 to 2016 in Brazil / Tendências no transplante de córnea de 2001 a 2016 no Brasil

ABSTRACT A retrospective and analytical study was conducted by using data from the National Transplantation System on 184,575 corneal transplantations performed between January 2001 and December 2016 in order to analyze thetrends in corneal transplantation from 2001 to 2016 in Brazil. The Cochran-Armitage test, analysis of variance, and Duncan's multiple comparisons were used to verify the existence of trends, compare the mean values between regions, and verify the mean differences, respectively. A significance level of 5% was used for all tests. The analysis showed that there was a 2.4-fold increase in the number of corneal transplantations (from 6,193 [35.2 per million people (pmp)] to 14,641 [71 pmp]; p<0.001), a 50.7% increase in the efficacy of meeting the population's demand for corneal transplantation (from 35.3% to 53.2%; p<0.001), an 11-fold increase in the number of corneal transplantation centers (from 32 to 356), and a 2.5-fold increase in the number of corneal transplantation teams (from 276 to 688) in Brazil during the period studied. The waiting list for corneal transplantation decreased by 45.4% (from 23,549 [123 pmp] to 12,865 [62.4 pmp]; p<0.001), and the corneal transplantation teams performed about 19 corneal transplantations per year. The best indices were observed in the southern, midwestern, and southeastern regions, and the worst indices were in the northern and northeastern regions. Brazil has been improving its capacity to perform corneal transplantation in the past 16 years, although this improvement varies across regions. However, the population's demand for corneal transplantation is yet to be satisfactorily met, primarily due to the low number of corneal donations.

RESUMO Estudo retrospectivo e analítico, baseado em dados do Sistema Nacional de Transplantes de 184.575 transplantes de córnea realizados no período de janeiro de 2001 a dezembro de 2016, com o objetivo de analisar as tendências do transplante de córnea no Brasil de 2001 a 2016. Os testes de Cochran-Armitage, análise de variância e comparações múltiplas de duncan foram realizados para verificar a existência de tendência, comparação de médias entre regiões e verificação da diferença média, respectivamente. Um nível de significância de 5% foi utilizado em todos os testes. No Brasil, houve um aumento: de 2,4 vezes no número de transplantes de córnea (de 6.193 [35,2 pmp] para 14.641 [71 pmp] - p<0,001); de 50,7% na eficácia de atender a demanda populacional de transplantes de córnea (de 35,3% para 53,2% - p<0,001); de 11 vezes no número de centros de transplantes de córnea (de 32 para 356); e de 2,5 vezes no número de equipes transplantadoras de córnea (de 276 para 688). A lista de espera para o transplantes de córnea diminuiu em 45,4% (de 23.549 [123 pmp] para 12.865 [62,4 pmp] - p<0,001). A produtividade das equipes de córnea ao longo dos anos foi de 19 transplantes de córnea ao ano. Os melhores índices foram apresentados nas regiões Sul, Cen tro-Oeste e Sudeste e os piores no Norte e Nordeste. O Brasil, embora de forma heterogênea entre as regiões, vem melhorando a capacidade de realizar o transplante de córnea nos últimos 16 anos, porém a demanda populacional por transplante de córnea ainda não é adequadamente atendida, principalmente devido ao baixo número de doações de córnea.

Trends in corneal transplantation from 2001 to 2016 in Brazil.

A retrospective and analytical study was conducted by using data from the National Transplantation System on 184,575 corneal transplantations performed between January 2001 and December 2016 in order to analyze thetrends in corneal transplantation from 2001 to 2016 in Brazil. The Cochran-Armitage test, analysis of variance, and Duncan's multiple comparisons were used to verify the existence of trends, compare the mean values between regions, and verify the mean differences, respectively. A significance level of 5% was used for all tests. The analysis showed that there was a 2.4-fold increase in the number of corneal transplantations (from 6,193 [35.2 per million people (pmp)] to 14,641 [71 pmp]; p<0.001), a 50.7% increase in the efficacy of meeting the population's demand for corneal transplantation (from 35.3% to 53.2%; p<0.001), an 11-fold increase in the number of corneal transplantation centers (from 32 to 356), and a 2.5-fold increase in the number of corneal transplantation teams (from 276 to 688) in Brazil during the period studied. The waiting list for corneal transplantation decreased by 45.4% (from 23,549 [123 pmp] to 12,865 [62.4 pmp]; p<0.001), and the corneal transplantation teams performed about 19 corneal transplantations per year. The best indices were observed in the southern, midwestern, and southeastern regions, and the worst indices were in the northern and northeastern regions. Brazil has been improving its capacity to perform corneal transplantation in the past 16 years, although this improvement varies across regions. However, the population's demand for corneal transplantation is yet to be satisfactorily met, primarily due to the low number of corneal donations.

A 15-Year Review of Corneal Transplant in Brazil.

PURPOSE: To analyze 15-year of corneal transplant in Brazil. METHODS: Cross-sectional, retrospective, observational, and analytical study, between available data from the Brazilian Transplant Registry (January 2002-December 2016), collected by the Brazilian Association of Organ Transplantation was performed. The variables analyzed per year were number of corneal transplants, corneal transplants per million people (pmp), corneal transplant teams, and individuals on the waiting list for corneal transplants. Quantitative variables were expressed by their respective values. To verify the relationship of time with the variables, the Spearman correlation test was applied, adopting P<0.05 for rejection of the null hypothesis. RESULTS: Evaluation of the data from 2002 to 2016 revealed an increase in number of (1) corneal transplants (4,976-14,534-approximately 292% in 15 years; P<0.0001); (2) corneal transplants pmp (29.4-71.1 pmp; P<0.0001); (3) productivity of corneal transplants teams (40.1-79 transplants by each team per year; P=0.067); (4) effectiveness in meeting the Brazilian population demand for corneal transplants per year (18.2%-57.0%; P<0.0001); (5) potential donors (P<0.0001), effective donors (P<0.0001), and nondonors (P<0.0001). There was a reduction in the number of patients on the waiting list (19,189-10,923; P=0.056). CONCLUSION: Despite the progress in the last decade, the number of corneal transplants in Brazil cannot meet the growing population demand. Thus, this study suggests the implementation of more effective public policies of corneal transplants in Brazil, to minimize disparities in national territory, adequately meet the population demand, and reduce the time in waiting lists for corneal transplants.

Review of developments in corneal transplantation in the regions of Brazil - Evaluation of corneal transplants in Brazil.

The aim of this study was to identify inequalities in corneal donation and transplantation among the regions of Brazil. A transversal and retrospective study was specifically conducted using data from the Brazilian Transplant Registry collected by the Brazilian Association of Organ Transplantation between January 2002 and December 2014. The collected data were processed using descriptive statistical methods, and p<0.05 was the rate of rejection of the null hypothesis. From 2002 to 2014, there was an increase in the absolute number of corneal transplants, the annual rate of transplants per million people and the percentage of needed transplants performed in each of the five regions of Brazil. Family refusal and medical contraindication were the most frequent reasons for a lack of corneal donation. Although remarkable progress has been made in the last decade in each of the five Brazilian regions, health professionals' lack of preparation to approach families with donation requests at the death of a family member appears to be the main obstacle to increasing the number of corneal donations. Thus, the present study suggests the implementation of public policies to make corneal transplants more effective, particularly given that there are considerable disparities in the effectiveness with which regional needs are met and in health professionals' ability to perform transplants among the Brazilian regions, with higher rates in the South, Southeast and Midwest regions and lower rates in the North and Northeast regions.

Review of developments in corneal transplantation in the regions of Brazil - Evaluation of corneal transplants in Brazil

The aim of this study was to identify inequalities in corneal donation and transplantation among the regions of Brazil. A transversal and retrospective study was specifically conducted using data from the Brazilian Transplant Registry collected by the Brazilian Association of Organ Transplantation between January 2002 and December 2014. The collected data were processed using descriptive statistical methods, and p<0.05 was the rate of rejection of the null hypothesis. From 2002 to 2014, there was an increase in the absolute number of corneal transplants, the annual rate of transplants per million people and the percentage of needed transplants performed in each of the five regions of Brazil. Family refusal and medical contraindication were the most frequent reasons for a lack of corneal donation. Although remarkable progress has been made in the last decade in each of the five Brazilian regions, health professionals’ lack of preparation to approach families with donation requests at the death of a family member appears to be the main obstacle to increasing the number of corneal donations. Thus, the present study suggests the implementation of public policies to make corneal transplants more effective, particularly given that there are considerable disparities in the effectiveness with which regional needs are met and in health professionals’ ability to perform transplants among the Brazilian regions, with higher rates in the South, Southeast and Midwest regions and lower rates in the North and Northeast regions.

Avaliação das urgências oftalmológicas em um hospital público de referência em Pernambuco / Evaluation of ophthalmic emergencies in a public reference hospital in Pernambuco

RESUMO Objetivo: Avaliar as urgências oftalmológicas em um hospital público de referência de Pernambuco. Métodos: Estudo transversal e retrospectivo, com 26.358 pacientes atendidos na emergência oftalmológica da Fundação Altino Ventura , no período janeiro a junho de 2013. Os dados foram coletados por meio de protocolos baseados nas fichas de cadastro eletrônicas da emergência oftalmológica. Resultados: Observou-se que 52,5% dos indivíduos eram do gênero masculino e 42,5% encontravam-se na faixa etária de 21 a 40 anos; 90,8% eram provenientes da região Metropolitana do Recife e 55% dos casos foram classificados como de baixa gravidade. Os diagnósticos mais frequentes foram conjuntivite (35,17%) e trauma ocular (19,25%). Conclusão: Houve prevalência de pacientes do gênero masculino, na faixa etária de 21 a 40 anos, proveniente da região Metropolitana do Recife, classificado como baixa gravidade, atendidos no mês de janeiro, na segunda-feira, com o diagnóstico de conjuntivite, seguida por trauma ocular.

ABSTRACT Purpose: To evaluate ophthalmological emergencies in a public reference hospital in Pernambuco. Methods: Cross-sectional retrospective study with 26.358 patients attended in the ophthalmic emergency Altino Ventura Foundation, in the period january to june 2013. Data were collected using protocols based on electronic registration forms of ophthalmological emergency Results: It was observed that 52.5% of patients were male, 42.5% were aged 21-40 years; 90.8% were from the region metropolitan area of Recife; 55% classified as less severe. The main diagnoses were conjunctivitis (35.17%) and ocular trauma (19.25%). Conclusion: The prevalence of male patients, aged 21-40 years, from the metropolitan area of Recife, classified as low complexity, attended in January, on Monday, with the diagnosis of conjunctivitis, followed by ocular trauma.

Safety of warfarin therapy during cataract surgery under topical anesthesia.

PURPOSE: To analyze the safety of warfarin therapy during cataract surgery under topical anesthesia. METHODS: This was a prospective nonrandomized comparative study of 60 eyes of 60 patients treated with or without concurrent oral warfarin anticoagulant therapy, referred for cataract surgery under topical anesthesia. The sample included a treatment (n=30) and a control (n=30) group. RESULTS: There were no records of intraoperative or postoperative intracameral bleeding complications in both the groups. At 1-month postoperative follow-up, 90.0% of patients presented spectacle-corrected visual acuity of at least 20/40. CONCLUSION: Cataract surgery by phacoemulsification with topical anesthesia can be successfully conducted without discontinuing warfarin.

Safety of warfarin therapy during cataract surgery under topical anesthesia / Segurança da terapia com varfarina durante cirurgia de catarata com anestesia tópica

ABSTRACT Purpose: To analyze the safety of warfarin therapy during cataract surgery under topical anesthesia. Methods: This was a prospective nonrandomized comparative study of 60 eyes of 60 patients treated with or without concurrent oral warfarin anticoagulant therapy, referred for cataract surgery under topical anesthesia. The sample included a treatment (n=30) and a control (n=30) group. Results: There were no records of intraoperative or postoperative intracameral bleeding complications in both the groups. At 1-month postoperative follow-up, 90.0% of patients presented spectacle-corrected visual acuity of at least 20/40. Conclusion: Cataract surgery by phacoemulsification with topical anesthesia can be successfully conducted without discontinuing warfarin. .

RESUMO Objetivo: Avaliar a segurança da cirurgia de catarata com anestesia tópica em pacientes em uso de varfarina. Métodos: Estudo comparativo não aleatorizado, prospectivo de 30 olhos de 30 indivíduos sob terapia anticoagulante por via oral com Varfarina que se submeteram à cirurgia de catarata com anestesia tópica. O grupo controle foi composto por 30 olhos de 30 pacientes, com indicação de cirurgia de catarata, que não faziam uso de terapia anticoagulante. Resultados: Não houve registro de complicações hemorrágicas intracamerais transoperatórias ou pós-operatórias em ambos os grupos. Na visita pós-operatória de 30 dias, 90,0% dos pacientes apresentavam acuidade visual corrigida por óculos de pelo menos 20/40. Conclusão: A cirurgia de catarata por facoemulsificação com anestesia tópica pode ser realizada com sucesso sem interrupção da terapia com varfarina. .

Evaluation of the care characteristics of ophthalmic emergencies in a public hospital in greater São Paulo / Avaliação das características do atendimento de urgências oftalmológicas em um hospital público da Grande São Paulo

Purpose: Evaluate the characteristics of patients seen in the emergency department of ophthalmology in order to identify measures to improve the effectiveness of care and guide the enhancement of other emergency services. Methods: Cross-sectional, observational study with 300 patients treated at the Municipal Hospital of Santo Andre - Sao Paulo from 15 to 22 august 2011. Data were collected through interviews with patients based on a questionnaire. Results: It was observed that 73.7% lived at a distance of up to 20 km from the hospital and 71.6% of real emergencies and 61.3% of false emergencies sought treatment within a week of the onset of symptoms. Conclusions: Considered the need to provide information to the population about the type and severity of ocular emergencies, with emphasis on prevention and the importance of the most prevalent diseases such as corneal foreign body and corneal ulcer, and health policies aimed at creation of regional centers of specialized care in order to minimize barriers to access and increase the speed in the treatment of ocular emergencies.

Objetivo: Avaliar as características dos pacientes atendidos no pronto socorro de oftalmologia, a fim de identificar medidas que melhorem a eficácia do atendimento e nortear o aprimoramento de outros serviços de urgência. Métodos: Estudo transversal e observacional, com 300 pacientes, atendidos no Hospital Municipal de Santo André (SP), de 15 a 22 de agosto de 2011. Os dados foram coletados por meio de avaliação clínica e de entrevistas com pacientes baseadas em um questionário. Resultados: Observou-se que 73,7% residiam a uma distância de até 20 km do hospital, 71,6% das urgências verdadeiras e 61,3% das urgências falsas procuraram atendimento em até uma semana do início dos sintomas. Conclusão: Considera-se a necessidade de disponibilizar para a população informações a respeito do tipo e da gravidade de urgências oculares, com ênfase na prevenção e na importância das doenças mais prevalentes, como corpo estranho corneano e úlcera de córnea, além de políticas de saúde direcionadas à criação de centros de atendimento especializados regionais, a fim de minimizar barreiras para acesso e aumentar a rapidez no tratamento de urgências oculares.

Analgesia preemptiva com nepafenaco 0, 1% na fotocoagulação da retina / Preemptive analgesia of nepafenac 0. 1% in retinal photocoagulation

Objetivo: Avaliar o efeito preemptivo com nepafenaco 0,1% em pacientes submetidos à fotocoagulação da retina para tratamento da retinopatia diabética proliferativa. Métodos: Trinta pacientes foram submetidos à fotocoagulação com laser de argônio em ambos os olhos. O olho contralateral de cada paciente foi o controle. O nepafenaco e o placebo foram utilizados 30 minutos antes da aplicação do laser. Ambos os olhos foram fotocoagulados no mesmo dia. A intensidade da dor foi avaliada por meio da escala analógica visual e da escala descritiva de dor. Resultados: A análise da interação instilação versus nepafenaco mostrou que os pacientes do grupo placebo apresentaram níveis de dor semelhantes em ambos os olhos, e os do grupo nepafenaco apresentaram redução importante do nível de dor no olho em que foi instilado a suspensão de 0,1% quando comparado ao olho contralateral que recebeu placebo (p=0,023). Conclusão: Este estudo sugere que a suspensão de 0,1% de nepafenaco foi útil na analgesia preemptiva de pacientes submetidos à fotocoagulação de retina quando comparada ao placebo. .

Objective: To evaluate the preemptive effect of nepafenac 0,1% in patients undergoing retinal photocoagulation for the treatment of proliferative diabetic retinopathy Methods: Thirty patients underwent argon laser photocoagulation in both eyes. The contralateral eye of each patient was the control. The nepafenac and placebo were used 30 minutes before the application of the laser. Both eyes were photocoagulated in the same day. Pain intensity was assessed by visual analog scale and descriptive pain scale Results: The analysis of the interaction instillation versus nepafenac showed that patients in the placebo group had similar levels of pain in both eyes, and the nepafenac group had significant reduction in pain in the eye that was instilled suspension of 0,1% when compared to the contralateral eye which received placebo (p = 0.023). Conclusion: This study suggests that a suspension of 0,1% nepafenac helpful for preemptive analgesia in patients undergoing retinal photocoagulation compared to placebo. .

Perfil epidemiológico de pacientes na fila de transplante de córnea no estado de Pernambuco - Brasil / Epidemiological profile of patients waiting for penetrating keratoplasty in state of Pernambuco - Brazil

Objetivo: Descrever o perfil epidemiológico de pacientes na fila de transplante de córnea no estado de Pernambuco, Brasil. Métodos: Estudo transversal e retrospectivo realizado no período 01/06/2011 a 31/05/2012, com 871 pacientes cadastrados na fila de espera para transplante de córnea na Central de Notificação, Captação e Distribuição de Órgãos de Pernambuco (CNCDO/PE). Os dados foram coletados por meio de protocolos baseados nas fichas de cadastro de receptor de córnea. Resultados: Em relação à frequência, obteve-se 54% do gênero feminino, 35% na faixa etária de 61 a 80 anos; 60% transplantados; 52% provenientes da região Metropolitana do Recife; 57% que aguardaram 1 a 6 meses o transplante; 82% com indicação de transplante óptico; 5% com prioridade na fila de espera (destes 48% por perfuração ocular) e 37% cujo centro transplantador era a Fundação Altino Ventura (FAV). As principais indicações para transplante de córnea foram leucoma (33%), ceratocone (22%) e ceratopatia bolhosa (18%). Conclusão: Verificou-se que a maioria dos pacientes encontra-se na faixa etária de 61 a 80 anos; era da Mesorregião Metropolitana de Recife; foi submetida ao transplante de córnea; aguardou de um a seis meses para realizar o transplante; teve como diagnóstico o leucoma, seguido por ceratocone e ceratopatia bolhosa; teve como indicação o transplante óptico e teve como centro transplantador a FAV. .

Purpose: To describe the epidemiological profile of patients waiting for penetrating keratoplasty in state of Pernambuco, Brazil. Methods: Transversal and retrospective study, with 871 patients, in the period of 06/01/2011 a 05/31/2012, were registered on the waiting list for corneal transplantation in the Central of Notification, Captation and Distribution of Organs (CNCDO) of Pernambuco. Registration forms of cornea receiving were used, adapted to the purposes of this research. Results: In relation to frequency, it was obtained 54% female, 35% aged 61 to 80 years; 60% transplanted; 52% from the metropolitan area of Recife; 57% that waited 1 to 6 months the transplant; 82% with optical indication for transplant, 5% with priority on the waiting list (48% of those with ocular perforation) and; 37% whose transplant center was the Fundação Altino Ventura (FAV). The main indications for corneal transplantation were leukoma (33%), keratoconus (22%) e bullous keratopathy (18%). Conclusion: It was found that most patients were aged 61 to 80 years; was from the metropolitan area of Recife; was submitted to corneal transplantation; waited for one to six months to do the transplantation; had the diagnosis leukoma, followed by keratoconus and bullous keratopathy; was indicated to transplantation optical and had the transplant center to FAV. .

Qualidade de vida de pacientes submetidos à cirurgia bariátrica, por meio da aplicação do questionário Baros / Quality of life of pacients submitted to bariatric surgery, by the application of baroquestionary

Objetivo: avaliar a qualidade de vida de pacientes submetidos à cirurgia bariátrica, no Hospital Ophir Loyola, emBelém do Pará. Método: estudo transversal, com 22 pacientes, submetidos à cirurgia bariátrica pela técnica do bypassgástrico, no período de outubro de 2002 a outubro de 2003. Para a realização da pesquisa, foi utilizado o questionárioBAROS que analisa três parâmetros: a perda do excesso de peso, a melhora da comorbidez e a melhora da qualidadede vida. Resultados: 82% sexo feminino; 100% com obesidade grau III no pré-operatório; 40,9% de obesidade grau Ino pós-operatório; 34% com osteoartrite, seguida de 18% de hipertensão no pré-operatório; 68,2% com todas as coafecçõesmaiores resolvidas e as outras melhoradas; 90,9% com auto-estima, 59,1% com disposição para atividadesfísicas; 81,8% com relacionamento social; 72,7% com disposição para o trabalho e 63,6% com interesse em sexo;todos estes aspectos muito melhorados e 59% obtiveram resultado excelente da cirurgia Conclusão: verificou-se entreos pacientes submetidos à cirurgia bariátrica: a prevalência do sexo feminino; a obesidade grau III no pré-operatório egrau I no pós-operatório; a osteoartrite, seguida de hipertensão como comorbidades mais freqüentes no pré-operatórioe todas as co-afecções maiores resolvidas e as outras melhoradas. Em relação à qualidade de vida, a auto-estima, adisposição para atividades físicas, o relacionamento social, a disposição para o trabalho e o interesse em sexo forammuito melhoradas, apontando que o resultado da cirurgia foi excelente

Objective: to evaluate the quality of life of pacients submitted to bariatric surgery, in Hospital Ophir Loyola, inBelém of Pará. Method: transversal study, with 22 patients, undergoing to the bariatric surgery by the technique ofthe gastric bypass, in the period of October of 2002 until October of 2003. For the accomplishment of the research,BAROS questionary was used to analyzes three parameters: the loss of the weight excess, the improvement of thecomorbidity and the improvement of the quality of life. Results: 82% were feminine sex; 100% with obesitydegree III in the preoperative; 40,9% of obesity degree I in the postoperative; 34% with osteoarthritis, followed by18% of hypertension in the preoperative; 68,2% with all comorbidities biggest resolved and the others improved;90,9% with self-esteem, 59,1% with disposition for physical activities, 81,8% with social relationship, 72,7% withdisposition for work and 63,6% with interest in sex, all these aspects very improved and; 59% had gotten excelentresults of the surgery. Conclusion: it was verified among the patients submitted to the bariatric surgery: theprevalence of the feminine sex; the obesity degree III in the preoperative and degree I in the postoperative; theosteoarthritis, followed by hypertension as more frequent comorbidities in the preoperative and; all the biggestcomorbidities resolved and the others improved. About the quality of life, the self-esteem, the disposition for thephysical activities, the social relationship, the disposition for the work and the interest in sex were very improved,pointing that the result of the surgery was excellent.

Perfil epidemiológico de pacientes na fila de transplante penetrante de córnea no estado do Pará, Brasil / Epidemiological profile of patients waiting for penetrating keratoplasty in state of Pará, Brazil

OBJETIVO: Descrever o perfil epidemiológico de pacientes na fila de transplante penetrante de córnea no estado do Pará, Brasil. MÉTODOS: Estudo transversal e retrospectivo, com 1261 pacientes, no período de janeiro de 2001 a dezembro de 2009, cadastrados na fila de espera para transplante de córnea na Central de Notificação, Captação e Distribuição de Órgãos (CNCDO) do Pará. Os dados foram coletados por meio de protocolos baseados nas fichas de cadastro de receptor de córnea na CNCDO, adaptados aos objetivos desta pesquisa. RESULTADOS: Em relação à frequência, obteve-se 51 por cento do sexo masculino; 33,9 por cento na faixa etária de 61 a 80 anos; 18,6 por cento inscritos na CNCDO em 2009; 61 por cento com olho direito acometido; 56 por cento permaneceram ativos na fila; 51,7 por cento que aguardaram 1 a 3 anos o transplante e; 85 transplantes realizados em 2009. As principais indicações para transplante de córnea foram ceratopatia bolhosa (28,2 por cento), leucoma (22 por cento) e úlcera corneana (14,8 por cento). CONCLUSÃO: Verificou-se que não houve diferença entre a frequência dos sexos sendo que a maioria encontrava-se na faixa etária de 61 a 80 anos; inscrita na CNCDO no ano de 2009 (ano em que foi realizado o maior número de transplantes); com o olho direito acometido, permaneceram ativos na fila de espera. Entre os pacientes transplantados, atestou-se que o tempo em fila de espera para transplante de córnea foi longo e inadequado. Ademais, as principais indicações para transplante de córnea no estado do Pará foram ceratopatia bolhosa, leucoma e úlcera corneana.

PURPOSE: To describe the epidemiological profile of patients waiting for penetrating keratoplasty in state of Pará, Brazil. METHODS: Transversal and retrospective study, with 1261 patients, in the period of january 2001 until to december 2009, were registered on the waiting list for corneal transplantation in the Central Notification, Captation and Distribution of Organs (CNCDO) of Pará. Registration forms of cornea receiving were used, adapted to the purposes of this research. RESULTS: In relation to frequency, it was obtained 51 percent male; 33.9 percent aged 61 to 80 years; 18.6 percent enrolled in CNPDO in 2009; 61 percent with the right eye affected; 56 percent remained active in the list; 51.7 percent that waited 1 to 3 years the transplant and; 85 transplants performed in 2009. The main indications for corneal transplantation were bullous keratopathy (28.2 percent), scarring (22 percent) and corneal ulcer (14.8 percent). CONCLUSION: There was no difference between the frequency of the sexes, the majority were aged 61 to 80 years, entered into the CNPDO in the year 2009 (the year it was held the largest number of transplants), with the right eye was affected, and who remained active in the waiting list. Among the transplanted patients, it was certified that the time in the waiting list for corneal transplantation was long and inappropriate. Furthermore, the main indications for corneal transplantation in state of Pará were bullous keratopathy, scarring and corneal ulcer.